Heart weight/body weight ratio (a), cardiac output (b), left ventricular fractional shortening (c) and heart rate (d) in untreated sham-operated Hannover Sprague-Dawley (HanSD + water) rats, in HanSD rats treated with soluble epoxide hydrolase inhibitor (sEHi) (HanSD + sEHi), in HanSD rats treated with angiotensin-converting enzyme inhibitor (ACEi) (HanSD + ACEi), in untreated HanSD rats with aorto-caval fistula (ACF HanSD + water), in ACF HanSD rats treated with sEHi (ACF HanSD + sEHi) and in ACF HanSD rats treated with ACEi (ACF HanSD + ACEi). * P<0.05 compared with HanSD + water.