Table 1. Characteristicsa of cases and controls, AACES (N=1272).
Cases (n=541) | Controls (n=731) | ||
---|---|---|---|
N (%) | N (%) | P-value | |
Age, yearsb | |||
<50 | 124 (23.1) | 198 (27.1) | 0.02 |
50–59 | 188 (35.1) | 272 (37.2) | |
60–69 | 143 (26.7) | 189 (25.8) | |
70+ | 81 (15.1) | 72 (9.9) | |
Education | |||
⩽High school | 242 (44.7) | 271 (37.1) | 0.02 |
Some post high school training | 139 (25.7) | 207 (28.3) | |
College or graduate degree | 160 (29.6) | 253 (34.6) | |
Income | |||
<$25 000 | 254 (47.9) | 320 (44.3) | 0.18 |
$25 000–$49 999 | 130 (24.5) | 162 (22.4) | |
$50 000–$74 999 | 76 (14.4) | 121 (16.7) | |
$75 000+ | 70 (13.2) | 120 (16.6) | |
Parity (number of live births) | |||
Nulliparous | 105 (19.4) | 93 (12.7) | 0.01 |
1 | 101 (18.7) | 137 (18.7) | |
2 | 123 (22.7) | 194 (26.6) | |
3+ | 212 (39.2) | 307 (42.0) | |
Family history of breast or ovarian cancer | |||
No | 383 (72.5) | 577 (81.6) | 0.0002 |
Yes | 145 (27.5) | 130 (18.4) | |
Tubal ligation | |||
No | 351 (64.9) | 431 (59.0) | 0.03 |
Yes | 190 (35.1) | 300 (41.0) | |
BMI (kg m−2) | |||
<25 (underweight and normal weight) | 79 (14.7) | 136 (18.6) | 0.16 |
25–29.9 (overweight) | 139 (25.8) | 189 (25.9) | |
30+ (obese) | 320 (59.5) | 405 (55.5) | |
Oral contraceptive use | |||
Never | 163 (30.1) | 151 (20.7) | 0.0001 |
Ever | 378 (69.9) | 580 (79.3) | |
Menopausal status | |||
Pre-menopausal | 84 (15.6) | 134 (18.4) | 0.29 |
Peri-menopausal | 73 (13.5) | 84 (11.5) | |
Post-menopausal | 382 (70.9) | 511 (70.1) | |
Endometriosis | |||
No | 476 (88.6) | 696 (95.2) | 0.00001 |
Yes | 61 (11.4) | 35 (4.8) | |
Pelvic inflammatory disease | |||
No | 491 (91.4) | 692 (94.9) | 0.01 |
Yes | 46 (8.6) | 37 (5.1) | |
Mild intensity physical activity | |||
No | 389 (72.3) | 462 (63.2) | 0.0007 |
Yes | 149 (27.7) | 269 (36.8) | |
Moderate or strenuous intensity physical activity | |||
No | 301 (55.7) | 426 (58.3) | 0.37 |
Yes | 239 (44.3) | 305 (41.7) | |
Histologic subtype | |||
Serous | 367 (72.8) | ||
Mucinous | 24 (4.7) | ||
Endometrioid | 70 (13.9) | ||
Clear cell | 12 (2.4) | ||
Mixed | 14 (2.8) | ||
Other | 17 (3.4) |
Abbreviations: AACES=African American Cancer Epidemiology Study; BMI=body mass index.
Missing data on age for 5 women, income for 19 women, family history of a first-degree relative with breast or ovarian cancer for 37 women, BMI for 4 women, menopausal status for 4 women, endometriosis for 4 women, pelvic inflammatory disease for 6 women, mild intensity physical activity for 3 women, and moderate or strenuous intensity physical activity for 1 woman, and 37 cases for histologic subtype.
Age at diagnosis for cases and age at the time of interview for controls.