Table 2. Adjusted odds ratio for all oropharyngeal cancer cases and by subsite compared with controlsa.
Oropharyngeal cancer |
Base of tongue cancer |
Tonsil cancer |
||||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
Tonsillectomy | ||||||
No | Ref | – | Ref | – | Ref | – |
Yes | 0.63 (0.47–0.85) | 0.003 | 1.95 (1.25–3.06) | 0.003 | 0.22 (0.13–0.36) | <0.001 |
Number of sexual partners | ||||||
0–1 | Ref | – | Ref | – | Ref | – |
2–5 | 2.44 (1.40–4.27) | 0.002 | 2.1 (0.84–5.21) | 0.110 | 3.44 (1.5–7.91) | 0.004 |
6–14 | 3.81 (2.19–6.60) | <0.001 | 3.42 (1.42–8.27) | 0.006 | 5.69 (2.49–13) | <0.001 |
14+ | 4.65 (2.65–8.18) | <0.001 | 3.75 (1.52–9.21) | 0.004 | 7.73 (3.33–17.96) | <0.001 |
Education | ||||||
Some High School | Ref | – | Ref | – | Ref | – |
Completed High School | 0.61 (0.41–0.91) | –0.015 | 0.67 (0.34–1.32) | –0.248 | 0.59 (0.36–0.97) | –0.037 |
Some College and above | 0.45 (0.31–0.66) | <0.001 | 0.54 (0.29–1.03) | 0.061 | 0.4 (0.25–0.64) | <0.001 |
Pack-years | ||||||
<10 Pack-years | Ref | – | Ref | – | Ref | – |
⩾10 Pack-years | 2.2 (1.62–2.97) | <0.001 | 1.91 (1.18–3.09) | 0.009 | 2.23 (1.5–3.32) | <0.001 |
Insurance | ||||||
Private | Ref | – | Ref | – | Ref | – |
Medicaid/Medicare | 0.84 (0.57–1.25) | 0.393 | 0.59 (0.3–1.13) | 0.113 | 0.78 (0.46–1.31) | 0.341 |
None | 0.92 (0.55–1.53) | 0.743 | 0.86 (0.37–1.98) | 0.717 | 0.93 (0.51–1.72) | 0.823 |
Other | 0.7 (0.45–1.09) | 0.112 | 0.6 (0.3–1.19) | 0.1434 | 0.81 (0.47–1.41) | 0.464 |
Alcohol | ||||||
⩽1 Drink per week | Ref | – | Ref | – | Ref | – |
>1 Drink per week | 1.72 (1.16–2.56) | 0.007 | 1.23 (0.67–2.27) | 0.503 | 1.67 (0.98–2.84) | 0.058 |
Abbreviations: CI=confidence interval; OR=odds ratio; Ref=reference value.
Odds ratios are all mutually adjusted for in addition to matching factors (age, race, and gender).