Table I.
Composition of Boswellia Olegum Resin Gastroretentive (BR-GR) Tablet Formulations
| Formulaea | Formula code | HPMC | SCMC | PC | CP | Lactose |
|---|---|---|---|---|---|---|
| HPMC | HPMC | 150 | 60 | |||
| SCMC | SCMC | 150 | 60 | |||
| Pectin | PC | 150 | 60 | |||
| Carbopol | CP | 150 | 60 | |||
| HPMC-carbopol 1:2 | HCP12 | 50 | 100 | 60 | ||
| HPMC-carbopol 1:1 | HCP11 | 75 | 75 | 60 | ||
| HPMC-carbopol 2:1 | HCP21 | 100 | 50 | 60 | ||
| SCMC-carbopol 1:2 | SCP12 | 50 | 100 | 60 | ||
| SCMC-carbopol 1:1 | SCP11 | 75 | 75 | 60 | ||
| SCMC-carbopol 2:1 | SCP21 | 100 | 50 | 60 | ||
| Pectin-carbopol 1:2 | PCP12 | 50 | 100 | 60 | ||
| Pectin-carbopol 1:1 | PCP11 | 75 | 75 | 60 | ||
| Pectin-carbopol 2:1 | PCP21 | 100 | 50 | 60 | ||
| Control | C | 270 | ||||
| Control-1 | C1 | 210 |
HPMC hydroxypropyl methylcellulose, SCMC sodium carboxymethyl cellulose, PC pectin, CP carbopol
aAll formulae contain 150 mg Boswellia gum resin (BR), and 1% magnesium stearate. All formulae contain sodium bicarbonate (60 mg) except C