Table III.

Kinetic Modeling of Drug Release Profiles

Formula code	Zero order	First order	Higuchi model	Korsmeyer–Peppas		Drug transport mechanism
	Correlation coefficient (r 2)			r 2	Diffusional exponent (n)
HPMC	0.976	0.841	0.942	0.997	0.727	Non-Fickian
SCMC	0.938	0.925	0.954	0.995	0.666	Non-Fickian
PC	0.916	0.947	0.958	0.997	0.702	Non-Fickian
CP	0.948	0.952	0.870	0.964	0.656	Non-Fickian
HCP 12	0.961	0.968	0.932	0.969	0.626	Non-Fickian
HCP 11	0.961	0.993	0.985	0.995	0.677	Non-Fickian
HCP 21	0.901	0.990	0.959	0.998	0.698	Non-Fickian
SCP 12	0.971	0.927	0.878	0.974	0.587	Non-Fickian
SCP 11	0.997	0.970	0.975	0.998	0.636	Non-Fickian
SCP 21	0.991	0.951	0.965	0.999	0.619	Non-Fickian
PCP 12	0.958	0.990	0.989	0.998	0.693	Non-Fickian
PCP 11	0.981	0.985	0.976	0.996	0.671	Non-Fickian
PCP 21	0.980	0.986	0.979	0.995	0.667	Non-Fickian

HPMC hydroxypropyl methylcellulose, SCMC sodium carboxymethyl cellulose, PC pectin, CP carbopol