Table I.
Central composite design for the optimization of entrapment efficiency (%) along with coded and actual values of the independent variables
| Experimental run | Coded variables | Process variables | Response Y |
||||
|---|---|---|---|---|---|---|---|
| X1 | X2 | X3 | X1 | X2 | X3 | ||
| R1 | −1 | −1 | −1 | 500 | 1.0 | 1:2 | 68.22 |
| R2 | 1 | −1 | −1 | 1500 | 1.0 | 1:2 | 69.01 |
| R3 | −1 | 1 | −1 | 500 | 2.0 | 1:2 | 71.73 |
| R4 | 1 | 1 | −1 | 1500 | 2.0 | 1:2 | 71.95 |
| R5 | −1 | −1 | 1 | 500 | 1.0 | 3:2 | 74.23 |
| R6 | 1 | −1 | 1 | 1500 | 1.0 | 3:2 | 75.1 |
| R7 | −1 | 1 | 1 | 500 | 2.0 | 3:2 | 77.09 |
| R8 | 1 | 1 | 1 | 1500 | 2.0 | 3:2 | 78.22 |
| R9 | −1.68 | 0 | 0 | 160 | 1.5 | 1:1 | 77.07 |
| R10 | 1.68 | 0 | 0 | 1840 | 1.5 | 1:1 | 79.44 |
| R11 | 0 | −1.68 | 0 | 1000 | 0.66 | 1:1 | 70.18 |
| R12 | 0 | 1.68 | 0 | 1000 | 2.34 | 1:1 | 77.32 |
| R13 | 0 | 0 | −1.68 | 1000 | 1.5 | 4:25 | 65.12 |
| R14 | 0 | 0 | 1.68 | 1000 | 1.5 | 46:25 | 80.02 |
| R15 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 81.68 |
| R16 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 81.74 |
| R17 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 80.57 |
| R18 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 80.52 |
| R19 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 80.05 |
| R20 | 0 | 0 | 0 | 1000 | 1.5 | 1:1 | 80.02 |
X1 Stirring rate for emulsification (rpm), X2 concentration of sodium hydroxide (%), X3 MVO-to-chitosan ratio, Y Entrapment efficiency (%)