a Dissolution profiles of carvedilol from Dilatrend® tablets in phosphate buffers of pH 6.8 of various concentrations (6.25, 12.5, 25, 50, and 100 mM), and in double-distilled water. Data are represented as the mean ± SD (n = 5). b pH profiles during dissolution studies of carvedilol from Dilatrend® tablets in phosphate buffers of pH 6.8 of various concentrations (6.25, 12.5, 25, 50, and 100 mM). Data are represented as the mean ± SD (n = 5)