Table I.
Vehicle | Solubility (mg/mL) |
---|---|
Water | 3.24 ± 0.45 (×10−3) |
Oils | |
Labrafil M 2125 CS | 6.90 ± 0.38 |
Labrafil M 1944 CS | 3.88 ± 0.13 |
Capryol PGMC | 6.11 ± 0.38 |
Labrafac Lipophile WL 1349 | 0.34 ± 0.01 |
Peceol | 4.26 ± 0.57 |
Plurol | 2.18 ± 0.19 |
Maisine 35-1 | 1.97 ± 0.13 |
Sunflower seed oil | 0.13 ± 0.03 |
Castor oil | 0.53 ± 0.08 |
Surfactants and co-surfactants | |
Tween 20 | 21.90 ± 1.54 |
Tween 80 | 12.31 ± 1.16 |
Span 20 | 3.47 ± 0.15 |
Brij 30 | 21.84 ± 3.04 |
Capryol 90 | 20.95 ± 1.83 |
Labrasol | 64.65 ± 5.01 |
Transcutol HP | 96.89 ± 2.35 |
PEG 400 | 84.42 ± 1.13 |
Each value represents the mean ± S.D. (n = 3)
PEG polyethylene glycol