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. 2015 Aug 4;17(2):466–473. doi: 10.1208/s12249-015-0370-5

Table I.

Solubility of Erlotinib in Various Vehicles

Vehicle Solubility (mg/mL)
Water 3.24 ± 0.45 (×10−3)
Oils
 Labrafil M 2125 CS 6.90 ± 0.38
 Labrafil M 1944 CS 3.88 ± 0.13
 Capryol PGMC 6.11 ± 0.38
 Labrafac Lipophile WL 1349 0.34 ± 0.01
 Peceol 4.26 ± 0.57
 Plurol 2.18 ± 0.19
 Maisine 35-1 1.97 ± 0.13
 Sunflower seed oil 0.13 ± 0.03
 Castor oil 0.53 ± 0.08
Surfactants and co-surfactants
 Tween 20 21.90 ± 1.54
 Tween 80 12.31 ± 1.16
 Span 20 3.47 ± 0.15
 Brij 30 21.84 ± 3.04
 Capryol 90 20.95 ± 1.83
 Labrasol 64.65 ± 5.01
 Transcutol HP 96.89 ± 2.35
 PEG 400 84.42 ± 1.13

Each value represents the mean ± S.D. (n = 3)

PEG polyethylene glycol