Table 3. Comparative strengths and weaknesses of the serocatalytic and antibody acquisition models.

Serocatalytic models	Antibody acquisition models
Strengths	Strengths
• Effective at low transmission intensities when seropositivity is a good indicator of exposure.	• Uses all available data.
• Data from multiple antigens can be combined.	• Effective also at high transmission intensities where all individuals are seropositive.
Weaknesses	Weaknesses
• Data is compressed into a binary seronegative/seropositive state.	• Difficult to combine data from multiple antigens.
• Choice of seropositivity threshold is arbitrary.	• May not be applicable if data are not log-normally distributed, e.g. if there are many zero measurements.