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. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: J Dev Biol. 2014 Apr 10;2(2):84–100. doi: 10.3390/jdb2020084

Figure 1.

Figure 1

Comparison between the epicardium in embryonic development and the response to myocardial infarction. This schematic overview shows similarities and differences between the role of the epicardium in embryonic heart development and the post-MI response, which are discussed in this review. Dashed lines and red boxes indicate processes and aspects that are not fully established and are under debate.

Abbreviations: PEO: proepicardial organ; MI: myocardial infarction; EMT: epicardial-mesenchymal transition; SMC: smooth muscle cell; EC: endothelial cell; CM: cardiomyocyte; Tβ4: Thymosin-beta 4.