Table 3.
Self-monitored blood glucose profile – actual measurements (mmol/L; excursion change from baseline)
| Baseline excursion before and after meal glucose difference, mean (SD) | End point (≥32 weeks) excursion before and after meal glucose difference, mean (SD) | Change in excursion between baseline and end point (≥32 weeks), mean (SD) | |||
|---|---|---|---|---|---|
| Breakfast | Non-Asian | LM25 | 3.735 (2.434) | 1.855 (2.096) | −1.964 (2.637) |
| G+L | 3.969 (2.421) | 2.680 (1.993) | −1.246 (2.795) | ||
| Asian Indian | LM25 | 3.314 (2.567) | 2.467 (1.435) | −0.741 (2.664)* | |
| G+L | 3.347 (2.719) | 2.795 (1.919) | −0.393 (2.634) | ||
| East Asian | LM25 | 4.976 (2.456) | 2.978 (2.042) | −2.323 (2.949)** | |
| G+L | 5.174 (2.728) | 2.872 (2.551) | −2.214 (3.252)** | ||
| Lunch | Non-Asian | LM25 | 1.240 (2.636) | 2.030 (2.532) | 0.918 (2.857) |
| G+L | 1.568 (2.244) | 1.082 (2.116) | −0.274 (3.077) | ||
| Asian Indian | LM25 | 2.923 (2.704) | 2.517 (1.612) | −0.444 (3.148)* | |
| G+L | 2.373 (3.296) | 2.324 (1.773) | −0.062 (3.604) | ||
| East Asian | LM25 | 3.614 (2.599) | 3.130 (2.336) | −0.817 (3.185)*** | |
| G+L | 3.199 (2.964) | 1.967 (1.77) | −0.928 (2.506) | ||
| Dinner | Non-Asian | LM25 | 1.681 (2.712) | 0.854 (1.999) | −0.968 (2.708) |
| G+L | 2.038 (2.574) | 1.496 (2.259) | −0.635 (3.358) | ||
| Asian Indian | LM25 | 2.296 (2.912) | 2.363 (1.654) | −0.173 (3.214) | |
| G+L | 2.605 (2.785) | 2.381 (1.930) | −0.192 (3.160) | ||
| East Asian | LM25 | 3.177 (2.977) | 1.588 (2.721) | −1.606 (3.224) | |
| G+L | 2.517 (2.813) | 1.371 (2.644) | −1.416 (3.479) |
Notes:
*
Significant (P<0.05) difference between Asian Indian and non-Asian.
**
Significant (P<0.05) difference between East Asian and Asian Indian.
***
Significant (P<0.05) difference between East Asian and non-Asian.
Abbreviations: LM25, insulin lispro mix 25 (25% insulin and 75% insulin lispro protamine suspension); G+L, glargine plus lispro.