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. 2016 Aug 9;10:2535–2546. doi: 10.2147/DDDT.S110125

Table 1.

Bone biomechanical properties and serum biochemical analyses of lupus mice undergoing different treatments

Group WT group Lupus group GC group Sal group GC + Sal group
ULT (N) 20.68±2.25 14.32±1.96A 14.31±0.93A 16.87±2.03A,b,c 15.74±2.03A
YLD (N) 17.32±1.80 8.77±1.72A 8.49±0.58A 11.93+0.96A,b,c 10.61±2.32A
STIFF (N/mm) 138.29±14.6 50.5±5.33A 44.48±8.47A 68.82±10.01A,b,c 61.01±2.28A,b,c
TRACP 5b (U/L) 0.72±0.04 1.01±0.04A 1.05±0.06A 0.92±0.03A,B,C 0.96±0.02A,b,C
OPG (pg/mL) 209.31±27.04 77.85±12.77A 106.88±33.4A 208.8±34.8B,C 175.8±29.5B,C

Notes:

A

P<0.01 vs WT;

b

P<0.05 vs lupus;

B

P<0.01 vs lupus;

c

P<0.05 vs GC;

C

P<0.01 vs GC. Values are presented as mean ± SD.

Abbreviations: GC, glucocorticoid; Sal, salvianolate; SD, standard deviation; STIFF, stiffness; TRACP 5b, tartrate-resistant acid phosphatase 5b; ULT, ultimate load; WT, wild-type; YLD, yield load; OPG, osteoprotegerin.