Fig 1. Tissue concentration (pg/g) of Estrone and Estradiol in the noncancerous peripheral lung of SMLA cases and control cases using LC–MS/MS analysis.

Data are represented as box and whisker plots. The median value was represented by a horizontal line in the box pot, and gray box denoted the 75th (upper margin) and 25th percentiles of the values (lower margin), respectively. The upper and lower bars indicated the 90th and 10th percentiles, respectively. The statistical analysis was performed using a Mann-Whitney test. P-value less than 0.05 was considered significant.