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. 2016 Aug 15;11(8):e0160624. doi: 10.1371/journal.pone.0160624

Table 1. Requisite Closure Pressures.

Parameter Design Variations (all other parameters are held constant according to the standard design)
Membrane Thickness Channel Width Membrane Material Stiffness
200 μm 300 μm a 400 μm 500 μm 700 μm 900 μm 1100 μm 1300 μm Shore 26–28 Scale Aa Shore 35–40 Scale A Shore 57–63 Scale A
Control Pressure for Valve Closure (defined as ≤ 3.5 μL/s full flow) (psi) 15.0 28.8 36.3 42.5 30.0 26.3 25.0 22.5 28.8 35.0 >73.0b

Control pressure required for valve closure experimentally found for design variations. Listed stiffness values for the membrane material are sourced from Stratasys, Ltd material data sheets [24]. Closing pressures varied between different samples or different runs. The value represents the average control pressure at which the valve was closed (defined by a flow rate ≤ 3.5 uL/s) for all trials and printed valves. Error of ± 4.4 psi was found between trials of the same printed valve.

a Same sample data

b Valve did not close at control pressures tested. Flow measured at 73.4 psi was ~49% total flow and a single trial was conducted for this file.