Table 6. Adjusted hazard ratios (HR) for specific causes of death, adjusted for all variables in the table and stratified by cohort, deaths = 218.
| Adjusted HR (95% CI) | |||||||
|---|---|---|---|---|---|---|---|
| Cause of death | N (%) | Age ≥60 vs. <60 years | Female vs. Male | IDU vs. non-IDU | CD4 <200 vs. ≥200 cells/μL | HIV-1 RNA >50 vs. ≤50 copies/mL | Prior AIDS diagnosis 10 years after ART start vs. no AIDS |
| AIDS | 35 (16%) | 1.08 (0.33, 3.58) | 0.38 (0.13, 1.09) | 1.24 (0.52, 2.96) | 5.32 (2.49, 11.4) | 4.90 (2.30, 10.4) | 1.75 (1.16, 2.65) |
| Non-AIDS | 145 (67%) | 4.35 (2.97, 6.39) | 0.70 (0.45, 1.06) | 3.40 (2.26, 5.12) | 2.42 (1.49, 3.94) | 0.95 (0.62, 1.45) | 1.58 (1.27, 1.95) |
| Cardiovascular disease | 22 (10%) | 8.95 (3.63, 22.1) | 0.54 (0.16, 1.84) | 2.20 (0.59, 8.23) | 2.70 (0.71, 10.3) | 1.30 (0.44, 3.80) | 1.49 (0.84, 2.63) |
| Liver related | 18 (8%) | 1.65 (0.36, 7.50) | NA | 3.84 (1.31, 11.2) | 3.37 (1.11, 10.2) | 2.37 (0.87, 6.40) | 1.85 (1.02, 3.36) |
| Non-AIDS, non-liver malignancies | 45 (21%) | 3.39 (1.71, 6.70) | 0.81 (0.39, 1.68) | 1.79 (0.77, 4.20) | 1.62 (0.55, 4.80) | 0.58 (0.24, 1.42) | 0.88, 1.97) |
| Suicide/accident | 13 (6%) | 2.55 (0.65, 10.0) | 1.28 (0.39, 4.24) | 2.45 (0.62, 9.69) | 2.19 (0.42, 11.34) | 0.65 (0.13, 3.17) | 2.45 (1.25, 4.80) |
| Other* | 47 (22%) | 5.71 (2.84, 11.5) | 0.85 (0.42, 1.73) | 6.21 (3.14, 12.3) | 2.57 (1.11, 5.95) | 0.93 (0.44, 1.95) | 1.52 (1.04, 2.21) |
| Unknown | 38 (17%) | 4.72 (2.28, 9.77) | 0.50 (0.19, 1.27) | 3.33 (1.48, 7.53) | 3.38 (1.31, 8.74) | 0.61 (0.24, 1.55) | 1.15 (0.73, 1.83) |
IDU: injection drug use, CI: confidence interval
* Causes with fewer than 10 deaths: these were non-AIDS Infection (8); heart or vascular (6); respiratory disease (5); chronic obstructive pulmonary disease (4); renal failure (4); substance abuse (4); digestive system (4); central nervous system (3); lung embolus (1); other causes not included in CoDe classification system (15)