Fig 6. Rare cell-to-cell variation phenomena selected from conducted microfluidic analyses.

(A) Filamentous cells that grow but do not divide. (B) Formation of dark spots indicating aggregates in highly producing cells. (C) Dormant cells, which are significantly delayed or irresponsive in growth and expression. (D) Highly producing cells in an otherwise sparely producing population. (E) Overgrowth of slowly—dividing producer cells by rapidly growing non-producers. (F) Cell lysis of stressed overproducer cells or even rapidly growing non-producer cells. Red arrows indicate cells exhibiting the respective phenomena.