Table 3.
Nodal involvement at presentation by site and histology
| Site/histology | % nodal involvement (n) | p-value (compared with the reference standard) | Levels at highest risk |
|---|---|---|---|
| All small cell | 13.8 (29) | 0.26b | IIa, IIIb, contralaterala |
| Nasal/ethmoid SNUC | 16.7 (60) | 0.02a | IIa |
| Non-nasal/non-ethmoid SNUC | 32.7 (52) | <0.001a | Ia, IIa, IIIa, contralateralb, parotidb |
| T2 glottic larynx without supraglottic extension (reference standard) | 7.1 (562) | N/A | N/A |
| T2 glottic larynx with supraglottic extension | 9.7 (1490) | N/A | N/A |
Reference standard (T2 glottic without supra/subglottic involvement = 7.1%, n = 562).
p < 0.05.
p > 0.05, but absolute incidence higher than T2 glottic larynx with subglottic or supraglottic extension patients receive elective nodal treatment as standard of care.