Table 2.

Protective efficacy of antibody to the dPNAG glycoform against various microbial pathogens in mouse settings of infection.

S. aureus: lethal peritonitis, bacteremia, skin infection, pneumonia, keratitis

E. coli: lethal peritonitis, GI infection by Stx+ strains, systemic infection by multidrug resistant strains

Burkholderia cenocepacia: lethal peritonitis

A. baumannii: bacteremia and pneumonia

N. meningitidis serogroup B: neonatal mouse meningitis infection

S. pyogenes, skin infection leading to lethal systemic infection

L. monocytogenes: systemic infection

S. pneumoniae: pneumonia

C. albicans: keratitis

Plasmodium berghei ANKA: mouse malaria