Table 1. PBTs.
Transcript set | Biologic descriptiona | Interpretation |
---|---|---|
QCAT | Quantitative cytotoxic T cell – associated transcripts | Burden of effector T cells |
GRIT | IFNG – induced transcripts induced in rejecting tissue | Burden of IFNG effects |
Top 30 TCMR transcripts | Transcripts most specific for TCMR in human kidney transplants | Transcripts best reflecting cognate interactions between effector T cells and antigen-presenting cells in tissue |
QCMAT | Quantitative constitutive macrophage associated transcripts | Burden of macrophages |
IRRAT | Injury- and repair-induced transcripts in acutely injured parenchyma | Parenchymal response to acute injury with epithelial repair and remodeling. |
KT1 | Kidney parenchymal transcripts | Normal kidney parenchymal functions |
CT1 | Colon parenchymal transcripts | Normal colon parenchymal functions |
KT2 | Kidney parenchymal solute carrier transcripts | Normal kidney parenchymal solute transport |
CT2 | Colon parenchymal solute carrier transcripts | Normal colon parenchymal solute transport |
See Materials and Methods for references to transcript sets