Table 1. Subject characteristics and global DNA methylation among subjects cancer-free at first visit.

	LINE-1		Alu
	β	P-value	β	P-value
Age (years)	−0.002	0.76	−0.010	0.08
Body mass index (kg m−2)	0.001	0.94	0.022	0.022a
Race
Non-white	Ref.		Ref.
White	0.158	0.45	−0.0002	0.99
Education (years)
<13	Ref.		Ref.
13–16	−0.177	0.08	−0.010	0.92
>16	−0.001	0.99	−0.023	0.84
Smoking status
Never	Ref.		Ref.
Current	0.378	0.09	−0.032	0.87
Former	0.130	0.19	0.097	0.28
Cumulative smoking (pack-years)	0.003	0.09	0.001	0.74
Alcohol consumption
0–1 average drinks per day	Ref		Ref.
2+ average drinks per day	0.104	0.36	−0.05	0.61
White blood cell count	−0.010	0.62	−0.001	0.97
Neutrophils proportion	0.004	0.42	0.002	0.65

^aStatistically significant at P<0.05.