Table 4. Associations between rate of methylation change and cancer.
Cancer-free |
All cancer |
Prostate cancer |
|||||
---|---|---|---|---|---|---|---|
n | n | HR (95% CI) | P-value | n | HR (95% CI) | P-value | |
Incidence | |||||||
LINE-1 | 365 | 63 | 1.23 (0.29–5.11) | 0.77 | 13 | 0.75 (0.03–19.1) | 0.86 |
Alu | 3.62 (1.09–12.1) | 0.036a | 1.58 (0.11–22.2) | 0.73 | |||
Mortality | |||||||
LINE-1 | 389 | 23 | 3.88 (0.44–34.1) | 0.22 | 4 | 0.75 (0.03–19.1) | 0.86 |
Alu | 1.96 (0.37–10.2) | 0.43 | 9.97 (0.14–700) | 0.29 |
Abbreviations: CI=confidence interval; HR=hazard ratio.
Statistically significant at P<0.05.