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. 2016 Jul 14;115(4):497–504. doi: 10.1038/bjc.2016.213

Table 4. Correlates with patient characteristics.

Patient characteristic/statistical test Virus p16 EGFR
Age/PC NC NC NC
Gender/CS NC NC NC
Long-term survival/LH Univar: longer survival if HPV positive (P=0.00619). Multivar: longer survival if HPV positive or ‘any virus detected' (P=0.04075 and 0.01618). Shorter survival if Y73SV or HBV (P=0.01335 and 0.00543). Multivar: longer survival if p16 positive (P=0.02391) NC
Prior cancer/CS STLV-6 more likely (P=0.0444) NC NC
Smoking status/CS  Never-smoker  Former smoker  Current smoker Y73SV higher proportion in never-smokers (P=0.02368). Higher in current smokers (P=0.01378) NC
Pack-years/PC STLV-6 more likely present in the greater number of pack-years (P=0.03730). NC NC
Tissue storage time/PC Longer the storage, the less likely to find BLV and STLV-6 (P=0.028001 and 0.010301). NC NC

Abbreviations: BLV=bovine leukemia virus; CS=χ2-test; HPV=human papillomavirus; HBV=hepatitis B virus; LH=log hazard ratio; Multivar=multivariable; NC=no correlation; PC=Pearson coefficient test; STLV-6=Simian T-cell leukemia virus-6; Univar=univariable; Y73SV=Y73 sarcoma virus.