Table 1.
Characteristics of the patients by treatment group
| Variable | Subgroups | p-CAIR (n = 44) | RT-CH (n = 40) | p-value |
|---|---|---|---|---|
| Age (median: 57; range 40–76) (years) | <57 years | 22 (50.0%) | 19 (47.5%) | 0.85 |
| >57 years | 22 (50.0%) | 21 (52.5%) | ||
| Sex | M | 33 (75.0%) | 28 (70.01%) | 0.69 |
| F | 11 (25.0%) | 12 (30.0%) | ||
| Tumour site | Oral cavity | 21 (47.7%) | 21 (52.5%) | 0.71 |
| Oropharynx | 23 (52.3%) | 19 (47.5%) | ||
| cT stage | T1, T2 | 27 (61.4%) | 25 (62.5%) | 0.95 |
| T3, T4 | 17 (38.6%) | 15 (37.5%) | ||
| cN stage | cN0 | 13 (29.5%) | 8 (20.0%) | 0.93 |
| cN1–3 | 31 (70.5%) | 32 (80.0%) | ||
| Pathological margin | Negative | 29 (65.9%) | 31 (77.5%) | 0.25 |
| Positive | 15 (34.1%) | 9 (22.5%) | ||
| Grade | G1 | 5 (11.4%) | 8 (20.0%) | 0.82 |
| G2 | 30 (68.2%) | 23 (57.5%) | ||
| G3 | 3 (6.8%) | 5 (12.5%) | ||
| Uncertain | 6 (13.6%) | 4 (10.0%) | ||
| Number of invaded nodes | 0 | 11 (25.0%) | 11 (27.5%) | 0.76 |
| 1 | 10 (22.7%) | 10 (25.0%) | ||
| >1 | 21 (47.7%) | 18 (45.0%) | ||
| Uncertain | 2 (4.4%) | 1 (2.5%) | ||
| Interval surgery-XRT | ≤9 weeks | 10 (22.7%) | 8 (20.0%) | 0.59 |
| >9 weeks | 34 (77.3%) | 32 (80.0%) | ||
| ZUBROD | 0 | 18 (40.9%) | 19 (47.5%) | 0.60 |
| 1 | 26 (59.1%) | 21 (52.5%) |
cN, clinically assessed nodal stage; cT, clinically assessed tumour stage; F, female; M, male; p-CAIR, post-operative radiotherapy; XRT, radiotherapy; ZUBROD, general performance score.