Table 3.
Patient characteristics, S-100B categories and cranial CT (CCT) as well MRI findings of selected cases of the study group
Patient number | Age (years) | Gender | GCS on admission | Mechanism of injury | Risk factors | S-100B | CCT findings (n) | MRI findings (n) |
---|---|---|---|---|---|---|---|---|
1 | 40 | Female | 15 | Fall | LOC, nausea, severe headache, anticoagulants | Elevated | Contusion (1), SDH (1) | Contusions (2), SDH (1) |
2 | 26 | Female | 15 | MVA | LOC, PTA, nausea, severe headache, dizziness | Elevated | Fracture (1) | Contusions (2), SAH (3) |
3 | 42 | Male | 15 | Fall | Intoxication | Elevated | SAH (1) | SAH (1), contusions (2) |
4 | 22 | Male | 15 | Fall | LOC, PTA | Elevated | Fracture (1), EDH (1) | EDH (1) |
5 | 73 | Female | 15 | MVA | LOC, PTA, severe headache, age over 60 years | Elevated | SDH (1) | SDH (1), contusions (1), SAH (1) |
6 | 80 | Female | 15 | Fall | Dizziness, anticoagulants, age over 60 years | Elevated | Contusion (1) | Cavernoma |
7 | 54 | Female | 15 | Fall | LOC, PTA, dizziness, intoxication | Elevated | Contusion (1) | Negative |
8 | 33 | Male | 14 | Fall | LOC, PTA, intoxication | Elevated | Contusion (1) | Negative |
9 | 56 | Male | 15 | MVA | PTA, LOC | Elevated | Contusion (1) | Negative |
10 | 44 | Male | 15 | MVA | LOC, severe headache | Not elevated | Contusion (1) | Negative |
11 | 39 | Male | 15 | MVA | Severe headache, dizziness | Not elevated | Contusion (1) | Negative |
12 | 44 | Male | 15 | MVA | LOC, severe headache | Not elevated | Contusion (1) | Negative |
EDH, epidural haemorrhage; GCS, Glasgow Coma Scale; LOC, loss of consciousness; MVA, motor vehicle accident; PTA, post-traumatic amnesia; SAH, subarachnoid haemorrhage; SDH, subdural haemorrhage.
Elevated S-100B: concentrations >0.1 μg l−1.
Cases 1–5 are patients with positive MRI findings. MRI shows additional trauma-related lesions compared with CCT (additional findings appear in bold type). Skull fractures were not diagnosed by MRI. Case 6 represents an example where MRI clearly distinguished a cavernoma from a suspected contusion. Cases 7–9 are patients with false-positive CCT findings in patients with elevated S-100B concentrations. Cases 10–12 are patients without elevated S-100B concentrations where the initial CCT was assessed as pathologic with suspicion of intracerebral contusions; MRI was able to rule out intracranial trauma, and therefore, these findings were interpreted as artefacts, in retrospect.