Table 1.
Radiological characteristics of all intraductal papillary mucinous neoplasms (IPMNs)
| Radiological characteristics | Malignant (n = 191) | Benign (n = 193) | pb | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|---|
| Invasive growth | 82 (42.9) | 17 (8.8) | <0.001 | 42.9 | 91.2 | 82.8 | 61.8 | 67.2 |
| Arterial infiltration | 19 (9.9) | 1 (0.5) | 0.003 | 9.9 | 99.5 | 95.0 | 52.8 | 54.9 |
| Central scarring | 7 (3.7) | 4 (2.0) | 0.350 | 3.7 | 97.5 | 63.6 | 50.7 | 51.0 |
| Venous infiltration | 58 (30.3) | 11 (5.7) | <0.001 | 30.4 | 94.3 | 84.1 | 57.8 | 62.5 |
| Calcification | 19 (9.9) | 5 (2.6) | 0.003 | 11 | 97 | 79.2 | 52.2 | 53.9 |
| Solid component | 104 (54.5) | 26 (13.5) | <0.001 | 54.5 | 86.5 | 80.0 | 65.8 | 70.6 |
| Lymphadenopathy | 40 (20.9) | 8 (4.1) | <0.001 | 20.9 | 95.9 | 83.3 | 55.1 | 58.6 |
| Bile duct dilation | 80 (41.9) | 3 (1.6) | <0.001 | 41.9 | 98.4 | 96.4 | 63.1 | 70.3 |
| Septum formation | 107 (56.0) | 74 (38.3) | 0.001 | 56 | 61.7 | 59.1 | 58.6 | 58.9 |
| Parenchymal atrophy | 107 (56.0) | 34 (17.6) | <0.001 | 56 | 82.4 | 75.9 | 65.4 | 69.2 |
| MD-IPMN | 33 (17.3) | 15 (7.8) | 0.006 | 17.3 | 19.2 | 68.8 | 53.0 | 55.0 |
| Mixed-type IPMN | 84 (44) | 45 (23.3) | <0.001 | 44 | 76.7 | 65.1 | 58.0 | 60.4 |
| Mixed or MD-IPMN | 117 (61.3) | 60 (31.1) | <0.001 | 68.9 | 61.3 | 66.1 | 64.3 | 65.1 |
| Location | ||||||||
| Head | 118 (61.8) | 138 (71.5) | 0.043 | 38.2 | 71.5 | 57.0 | 53.9 | 54.9 |
| Body | 32 (16.8) | 21 (10.9) | 0.095 | 16.8 | 89.1 | 60.4 | 52.0 | 53.1 |
| Tail | 33 (17.3) | 30 (15.5) | 0.647 | 17.3 | 84.5 | 5.0 | 16.0 | 51.0 |
| Throughout pancreas | 8 (4.2) | 1 (0.5) | 0.243 | 4.2 | 97.9 | 50.8 | 66.7 | 51.3 |
| MPD diametera,c (mm) | 8.12 (±1.03) | 4.41 (±0.52) | <0.001 | |||||
| Cyst sizea,c (mm) | 28.70 (±3.25) | 23.90 (±2.27) | 0.284 | |||||
| Age (years)a,d | 64.5 (±0.76) | 63.7 (±0.73) | 0.475 | |||||
| Gender | ||||||||
| Male | 100 (52.4) | 87 (45.1) | 0.154 | |||||
| Female | 91 (47.6) | 106 (54.9) | ||||||
MD-IPMN, main duct intraductal papillary mucinous neoplasm; MPD, main pancreatic duct; NPV, negative-predictive value; PPV, positive-predictive value.
Values in parentheses are percentages unless otherwise indicated.
a
Values are expressed in mean, standard deviations given in parentheses.
b
χ2 test.
c
Mann–Whitney U test.
d
Unpaired t test.