Table 4.
Univariate models | Multivariate model | ||||
---|---|---|---|---|---|
Variable | No. of first pregnancies/PY | Crude IRR (95% CI) | p | Adjusted IRR (95% CI) | p |
Center | 0.78 | ||||
CEPREF | 5/260.7 | Ref. | |||
Cocody University Hospital | 2/68.0 | 1.5 (0.3–7.9) | |||
Yopougon University Hospital | 6/452.4 | 0.7 (0.2–2.3) | |||
CIRBA | 2/156.9 | 0.7 (0.1–3.4) | |||
Age (time adjusted) (years) | 0.01 | <0.01 | |||
<15 | 1/493.5 | Ref. | Ref. | ||
≥15 | 14/444.5 | 15.5 (2.0–118.2) | 14.2 (1.9–108.2) | ||
Maternal orphan at baseline | 0.03 | 0.05 | |||
Yes | 12/490.1 | 3.7 (1.0–13.0) | 3.1 (0.9–11.0) | ||
No/unknown | 3/447.9 | Ref. | Ref. | ||
Paternal orphan at baseline | 0.37 | ||||
Yes | 4/352.1 | 0.6 (0.2–1.9) | |||
No/unknown | 11/585.9 | Ref. | |||
Underweight (weight-for-age z-score <−2SD) | |||||
Yes | 2/264.0 | Ref. | 0.17 | ||
No | 13/674.0 | 2.6 (0.6–11.3) | |||
Stunting (height-for-age z-score <−2SD) | |||||
Yes | 4/329.1 | Ref. | 0.49 | ||
No/unknown | 11/608.9 | 1.5 (0.5–4.7) | |||
Anemia (hemoglobin <12 g/dl) at baseline | |||||
Yes | 10/653.6 | 0.9 (0.2–4.3) | 0.87 | ||
No/unknown | 5/284.4 | Ref. | |||
CD4 (cells/mm3) at baseline | 0.50 | ||||
<350 | 5/241.0 | Ref. | |||
≥350 | 10/697.0 | 0.7 (0.2–2.0) | |||
On ART at baseline | 0.50 | ||||
Yes | 11/755.9 | 0.7 (0.2–2.1) | |||
No unknown | 4/182.1 | Ref. |
ART=anti-retroviral therapy; IRR=incidence rate ratio; PY=person-years.