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. 2016 Aug 16;6:31664. doi: 10.1038/srep31664

Figure 6. MPT0G066 suppresses human ovarian carcinoma growth and potentiates antineoplastic effects of cisplatin in ovarian cancer in vivo.

Figure 6

SKOV3 and A2780 xenograft nude mice were orally (po) treated with MPT0G066 (200 mg/kg) daily or intravenously (iv) administered cisplatin (5 mg/kg) once a week or combination or vehicle after tumor cell implantation. Tumor volume and Body weight of SKOV3 and A2780 xenografts were shown in (A,B). (C) Formalin-fixed paraffin-embedded sections from SKOV3 and A2780 were stained with H&E stain and phosphorylated JNK (Thr-183 and Tyr-185) antibody. The stained sections were used 200X magnification to observe via microscope.