Table 4. Distribution of the proportion of patients with intraretinal/subretinal fluid on optical coherence tomography examination at baseline and 12-month follow up.

	Baseline	12 Months	P-value
All patients (presence/72)	100% (72/72)	50% (36/72)	<0.0001
PRN regimen	100% (36/36)	42% (15/36)	<0.0001
Fixed regimen group (Loading phase+2q8)	100% (36/36)	58% (21/36)	<0.0001
PRN group vs fixed regimen group	(p: 1.00)	(p: 0.23)

Abbreviations: fixed regimen, loading phase+bimonthly injections; PRN, pro re nata strategy.

The intraretinal/subretinal fluid displayed a statistically significant decrease during the period study in both groups.