Figure 2. Mutation of c-Kit increases bone formation and bone resorption in growing male mice.

(A) Representative μCT images of cancellous (left) and cortical bone (right) from tibiae of 6-, 9-, and 13-week-old WT and W^sh/W^sh mice. (B) Histomorphometric analysis of cancellous bone in tibiae. (C) Serum concentration of P1NP and CTX (ng/ml). Results are mean ± SEM. *p < 0.05 versus WT.