Skip to main content
. 2016 Aug 16;6:30987. doi: 10.1038/srep30987

Figure 2. Predatory bacteria induce an IL-8, but not IL-1β response from corneal stromal keratocytes in vitro.

Figure 2

Pro-inflammatory cytokines IL-1β (A) and IL-8 (B) were measured by ELISA. Cell supernatants taken from keratocytes after 4 hours of incubation with medium only negative control (Mock), positive control Pseudomonas aeruginosa strain PA14 (MOI = 200), and experimental strains M. aeruginosavorus (Mica, MOI = 161), B. bacteriovorus strain HD100 (MOI = 594), and B. bacteriovorus strain 109J (MOI = 516). The average and standard deviation from n = 7 independent data points from 2 experiments are shown. Asterisks indicate significant differences (*p < 0.05, **p < 0.01, ***p < 0.001 determined using ANOVA with Tukey’s post-test). Limits of assay detection are denoted by the dotted horizontal lines.