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(A) The 662-kb B125 YAC DNA contains approximately 451 kb of 5′ and 211 kb of 3′ flanking sequences and all the exons of Gata3 gene. The lacZ cassette is inserted in the 2nd exon (9). (B) Embryonic day 10.5 Gata3Z/+ (a) and TgB125Z (b) embryos show similar lacZ expression patterns in the ureteric bud region (arrows) and the pharyngeal arch (arrowheads).
