Recommendations for lipid control

CV = cardiovascular; HDL-C = high-density lipoprotein cholesterol;

LDL-C = low-density lipoprotein cholesterol.

^aClass of recommendation.

^bLevel of evidence.

^cReference(s) supporting recommendations.

^dNon-HDL-C is a reasonable and practical alternative target because it does not require fasting. Non HDL-C secondary targets of <2.6, <3.3 and <3.8 mmol/L (<100, <130 and <145 mg/dL) are recommended for very high, high and low to moderate risk subjects, respectively See section 3a.7.10 for more details.

^eA view was expressed that primary care physicians might prefer a single LDL-C goal of 2.6 mmol/L (100 mg/dL). While accepting the simplicity of this approach and that it could be useful in some settings, there is better scientific support for the three targets matched to level of risk.

^fThis is the general recommendation for those at very high-risk. It should be noted that the evidence for patients with CKD is less strong.