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. Author manuscript; available in PMC: 2016 Aug 16.
Published in final edited form as: Microbes Infect. 2009 Aug 9;11(14-15):1106–1113. doi: 10.1016/j.micinf.2009.08.004

FIGURE 4. Effect of T. gondii on the replication of HIV-1 in co-infected tissues.

FIGURE 4

Blocks of human lymphoid tissues inoculated with 400 tachyzoites were co-infected with R5SF162 and X4LAI.04 HIV-1 or left singly infected with HIV-1 as a control. HIV-1 replication was monitored by measuring the concentration of p24 gag in the culture medium bathing infected tissue blocks. (A) The graph represents a typical kinetic of replication of HIV-1 R5SF162 (○) and X4LAI.04 (△) in singly infected tissues blocks or in tissue blocks co-infected with T. gondii and R5SF162 (●) or T. gondii and X4LAI.04 (▲). (B) Effects of T. gondii infection on total HIV-1 replication in co-infected tissues expressed as percentage of the cumulative HIV-1 replication in matched singly infected tissues. Each dot represents one experiment (n=63 for R5SF162, n=55 for X4LAI.04). The line represents the median and inter-quartile range of each distribution.