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. Author manuscript; available in PMC: 2016 Aug 16.
Published in final edited form as: Alcohol Clin Exp Res. 2011 May 20;35(9):1574–1583. doi: 10.1111/j.1530-0277.2011.01503.x

Fig. 2.

Fig. 2

Effect of ethanol on the expression of endoplasmic reticulum stress-inducible proteins (ERSIPs). (A) Postnatal day 7 mice were injected with ethanol as described. At 8 hours after the first injection, the cerebral cortex was removed, protein was extracted, and the expression of GRP78, ATF6, mesencephalic astrocyte-derived neurotrophic factor (MANF), CHOP, caspase-12, and the phosphorylation of eIF2α, IRE1α, PKR, and PERK was evaluated by immunoblotting. The results represent samples obtained from 4 control and 4 ethanol-exposed mouse pups. (B) The expression of ERSIPs was quantified by densitometry and normalized as described. The results were the mean ± SEM of 3 independent experiments. *Statistically significant difference from controls. EtOH, ethanol.