Table 5.
Pharmacokinetic parameters of the drug and Formulation 3 adminstered to rats
| Formulation |
C
pmax
(µg/mL) |
T
max
(hour) |
AUC
(0-24)
(mAU.s) |
MRT
(hour) |
|---|---|---|---|---|
| Drug | 810.15 (± 12.6) |
4 (±1.7) |
29997.59 (±4.66) |
48.16 (±2.105) |
| Formulation 3 | 977.51 (±19.4) |
2.5 (±0.3) |
86429.3 (±5.9) |
94.64 (±3.96) |
CPmax: maximum plasma concentration; Tmax: Time to maximum plasma concentration; AUC (0-24): Area under plasma concentration-time curve till 24 h; MRT: mean residence time