Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of liver injury and side effects of drugs between two groups
| Silymarin group | Placebo group | p-value | |
|---|---|---|---|
| Total | 35 | 35 | |
| Anorexia | 4 (11.4%) | 0 | 0.054 |
| Nausea | 2 (5.7%) | 3 (8.6%) | NS |
| Vomiting | 0 | 3 (8.6%) | NS |
| Abdominal pain | 4 (11.4%) | 3 (8.6%) | NS |
| Mild elevation of LFT |
1 (2.9%) | 2 (5.7%) | NS |
| DILI | 6 (17.1 %) | 3 (8.6%) | NS |
| Pruritus | 3 (8.6%) | 5(14.3%) | NS |
| Exanthema | 1 (2.9%) | 0 | NS |
| Diarrhea | 0 | 0 | - |
| Vertigo | 0 | 0 | - |
Abbreviations: LFT: liver function tests, DILI: drug induced liver injury, NS: no significant
