Table 2.
Drug modes of action and edge signs
Sign | DrugBank actions |
---|---|
Positive | agonist; partial agonist; activator; stimulator; inducer; |
positive allosteric modulator; potentiator; positive modulator | |
Negative | inhibitor; inhibitory allosteric modulator; inhibitor, competitive; antagonist; partial antagonist; negative modulator; inverse agonist; blocker; suppressor; desensitize the target; neutralizer; reducer |
Not classifiable | antibody; cofactor; modulator; binder; chaperone; cleavage; metabolizer; ligand; product of; component of; chelator; cross-linking/alkylation; intercalation; adduct; acetylation; allosteric modulator. |