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. 2016 Aug 15;15:142. doi: 10.1186/s12934-016-0542-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Pathway diagram of precursor synthesis for protein glycosylation and mevalonate pathway. Results show increases in upstream intermediates (red arrows) and significant decreases in proximal intermediates (green arrows) between the two scales, 10 and 10,000 L