Table 3.
Chemokines and chemokine receptors related to Treg trafficking
| Cancer | Chemokine receptor on Tregs | Chemokine | Origin of chemokines | Ref |
|---|---|---|---|---|
| Human | ||||
| Breast | CCR4 | CCL22 | Tumor cells | (59) |
| Cervical | ND | CXCL12 | Tumor cells | (68) |
| Colorectal | CCR4 | ND | ND | (60) |
| Oral squamous | CCR4 | ND | ND | (61) |
| Ovarian | CCR4 | CCL22 | TAMs | (63) |
| CCR10 | CCL28 | Tumor cells | (64) | |
| CXCR3 | ND | Tumor | (69) | |
| CXCR4 | CXCL12 | Tumor | (65) | |
| Pancreatic | CCR5 | CCL5 | Tumor cells | (66) |
| Hodgkin lymphoma | CCR4 | ND | ND | (62) |
| Mouse | ||||
| Colorectal | CCR6 | CCL20 | TAMs | (70) |
| Melanoma | CCR4 | CCL22 | Tumor | (67) |
| CCR5 | CCL3,4,5 | MDSCs | (71) | |
| Pancreatic | CCR5 | CCL5 | Tumor cells | (66) |
MDSCs, myeloid-derived suppressor cells; ND, not described; TAMs, tumor-associated macrophages.