Fig. 1.

The growth rate of mammary cancer 4T1 is delayed in Lgals3−/− mice. Balb/c Lgals3+/+ and Lgals3−/− females mice were inoculated with 105 4T1 mammary carcinoma cells in the fourth mammary fat pad. Representative image of 4T1 tumor in a (Lgals 3+/+) and b (Lgals3−/−) mice 28 days p.o.i. c Tumor volume of 4T1 tumors in Balb/c Lgals3+/+ and Lgals3−/− mice. d Representative image of 4T1 tumor excised from Balb/c Lgals3+/+ and Lgals3−/− mice 28 days p.o.i. e Tumor weight of 4T1 tumors in Balb/c Lgals3+/+ and Lgals3−/− mice 21 and 28 days p.o.i. f Representative image of 4T1 tumor ultrasonography from Balb/c Lgals3+/+ and Lgals3−/− mice 6 and 27 days p.o.i. g Tumor area of 4T1 tumors in Balb/c Lgals3+/+ and Lgals3−/− mice measured by ultrasonography. Data are the mean ± S.D., n = 4, three animals per group; *p < 0.05, **p < 0.01