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. 2016 Aug 15;14:240. doi: 10.1186/s12967-016-0996-4

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Three-dimensional m/z ratio-intensity maps. Those showed the seven significantly different peptides at 1723.7, 1851.4, 1886.5, 2331, 2995.7, 1370.4, and 3310.0 Da. Green, untreated; red, treated for 1 week; blue, treated for 4 weeks