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Proposed algorithm for treating peritoneal metastatic colorectal cancer. CC: Completeness of cytoreduction; CC-0/1: Complete macroscopic cytoreduction; IPC: Intraperitoneal chemotherapy; NIPS: Neoadjuvant intraperitoneal/systemic chemotherapy; PIPAC: Pressurized intraperitoneal aerosol chemotherapy; sCTx: Systemic chemotherapy; scattered lines indicate additional therapeutic options; HIPEC: Hyperthermic intraperitoneal chemotherapy.
