Table 1.

Staging systems for multiple myeloma

Stage	Durie-Salmon staging system	International staging system
I	Haemoglobin value >10 g dl−1 Normal serum calcium Bone radiography: normal bone structure or solitary bone plasmacytoma only Low levels of M protein in the blood or urine	Serum β2-microglobulin <3.5 mg l−1 Serum albumin ≥3.5 g dl−1
II	Not Stage I or III	Not Stage I or III
III	One or more of the following: Haemoglobin value <8.5 g dl−1 Serum calcium >12 mg dl−1 Advanced lytic bone lesions High M-component production rate	Serum β2-microglobulin ≥5.5 mg l−1