Table 1.
Patient characteristics.
| Parameter | No. (%)/[range] |
|---|---|
| Total | 291 |
| Median age, years | 70 [35–99] |
| Gender | |
| Male | 193 (66) |
| Female | 98 (34) |
| Race | |
| White | 259 (89) |
| African American | 13 (4) |
| Hispanic | 6 (2) |
| Others | 13 (4) |
| Clinical characteristics | |
| Median white blood cell count × 109/L | 4.80 [0.58–68] |
| Median hemoglobin, g/dl | 9.3 [3.7–14.3] |
| Median absolute neutrophil count × 109/L | 1.05 [0.01–24.8] |
| Median platelet × 103/mL | 73 [4–659] |
| Median bone marrow blast% | 9 [0–21] |
| Cytogenetics by IPSS-R | |
| Very good | 0 (0) |
| Good | 85 (29) |
| Inter | 45 (15) |
| Poor | 60 (21) |
| Very poor | 95 (33) |
| Not documented | 6 (2) |
| IPSS-R risk category | |
| Intermediate | 58 (20) |
| High | 107 (37) |
| Very high | 126 (43) |
| Not applicable | 6 (2) |
| IPSS risk category | |
| Intermediate-1 | 65 (22) |
| Intermediate-2 | 173 (59) |
| High | 47 (16) |
| Not applicable | 6 (2) |
| WHO classifications | |
| RCUD | 5 (2) |
| RCMD | 30 (10) |
| RARS | 3 (1) |
| RAEB-1 | 90 (31) |
| RAEB-2 | 135 (46) |
| MDS associated with isolated del (5q) | 2 (1) |
| MDS-U | 5 (2) |
| MDS/MPN | 13 (5) |
| Missing | 10 (4) |
Abbreviations: IPSS-R, International Prognostic Scoring System-Revised; IPSS, International Prognostic Scoring System; WHO, World Health Organization; RCUD, refractory cytopenia with unilineage dysplasia; RCMD, refractory cytopenia with multilineage dysplasia; RARS, refractory anemia with ring sideroblasts; RAEB, refractory anemia with excess blasts.