Table 1.
Histological characteristics of the uterine adenosarcomas included in this study, and sequencing analyses performed
| Case ID | Grade | Heterologous element | Stromal overgrowth | Tissue type | Whole-exome MPS | Targeted capture MPS | RNA-Sequencing |
|---|---|---|---|---|---|---|---|
| AS1 | Low | Absent | Absent | Frozen | Yes | ||
| AS3 | High | Present (rhabdomyoblastic differentiation) | Present | Frozen | Yes | Yes | |
| AS4 | Low | Absent | Absent | Frozen | Yes | Yes | |
| AS5 | Intermediate | Absent | Absent | Frozen | Yes | Yes | |
| AS6 | Intermediate | Present (osseous differentiation) | Present | Frozen | Yes | ||
| AS7 | Low | Absent (sex cord-like features) | Present | Frozen | Yes | Yes | |
| AS8 | Intermediate | Absent (sex cord-like features) | Present | Frozen | Yes | Yes | |
| BAS03 | Low | Absent | Absent | FFPE | Yes | ||
| BAS04 | Low | Absent | Absent | FFPE | Yes | ||
| BAS06 | High | Absent | Present | FFPE | Yes | ||
| BAS07 | Low | Absent | Absent | FFPE | Yes | ||
| BAS09 | Intermediate | Absent | Present | FFPE | Yes | ||
| BAS10 | Low | Absent | Absent | FFPE | Yes | ||
| BAS12 | Low | Absent | Absent | FFPE | Yes | ||
| BAS16 | Low | Present (rhabdomyoblastic differentiation) | Absent | FFPE | Yes | ||
| BAS18 | Low | Absent | Absent | FFPE | Yes | ||
| BAS19 | Low | Absent | Absent | FFPE | Yes | ||
| BAS22 | Low | Absent | Absent | FFPE | Yes | ||
| BAS27 | Low | Absent | Absent | FFPE | Yes | ||
| BAS30 | Low | Absent | Absent | FFPE | Yes |
FFPE, formalin-fixed, paraffin-embedded; MPS, massively parallel sequencing.