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The effects of NK1R inhibitor in a mouse model of kidney ischemia. At 30 min after treatment with the indicated doses of L-733,060, the mice were subjected to 25 min of bilateral renal ischemia. At 24 h following reperfusion, serum levels of creatinine (a), urea (b), neutrophil gelatinase-associated lipocalin (NGAL) (c), and osteopontin (d) were measured. The means with S.D. are shown. The asterisks indicate a significant (P<0.05) difference from the vehicle-treated group
