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. 2015 Apr 9;22(5):1009–1019. doi: 10.1093/jamia/ocv016

Table 4:

Top higher-order feature groups associated with follicular lymphoma

Follicular First Subgraph Group Follicular Second Subgraph Group
0.0308 interstitial lymphoid aggregates 0.0583 nodal architecture … effaced
0.0196 predominantly small … cell 0.0213 B-cells co-expressing BCL2, CD10
0.0171 paratrabecular lymphoid aggregates 0.0201 biopsy of lymph node
0.0149 focal 0.0091 sclerotic tissue
0.0127 cells in the follicles 0.0063 lymph node architecture effaced by … follicular proliferation
0.0117 large paratrabecular lymphoid aggregates 0.0061 sections show enlarged lymph nodes
0.0107 diffuse infiltrate of small lymphoid cells 0.0059 cell with reduced size
0.0093 infiltrate consisting of … lymphoid cells 0.0055 sections show … lymph nodes
0.0080 CD10+/− B-cell population 0.0045 residual … follicle center cells
0.0062 core needle biopsy 0.0043 cells stain positively for … BCL2
0.0050 follicles contain … centroblasts 0.0021 flow cytometry demonstrate … population
Follicular Third Subgraph Group Follicular Fourth Subgraph Group
0.0829 B-cells are negative for CD5 0.0642 lymphoid infiltration
0.0466 B-cells express 0.0269 atypical infiltration
0.0405 CD5−, … , CD23− 0.0267 dense lymphoid infiltration
0.0315 negative for CD10 0.0133 mucosa infiltration
0.0271 positive for CD23 0.0102 small lymphoid cells
0.0251 positive for CD10 0.0095 small lymphocytes
0.0148 positive for CD19, CD20, CD23 0.0084 cleaved centrocytes
0.0060 containing … large atypical cells … 0.0082 diffuse infiltrate of small lymphoid cells
0.0041 positive for CD3 0.0060 cells … in follicular dendritic pattern
0.0024 show B-cells are positive for CD3, CD20 0.0059 fibroadipose tissue
0.0018 CD5−, CD10−… B-cells 0.0044 dense infiltrate containing lymphoid cells

Subgraphs are translated to partial sentences. Partial sentences that are not mentioned in feature analysis are grayed out.