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. 2016 Feb 26;10(4):360–367. doi: 10.1080/19336918.2016.1155019

Figure 4.

Figure 4.

Light microscopy of a SCLC CTC tumorosphere. Adherent SCLC CTCs in tissue culture eventually start to form 3-dimensional structures under regular tissue culture conditions (A: BHGc10, left side of culture; magnification 100fold) which later grow into large tumorospheres (B: BHGc7, diameter of tumorosphere 560 µm; magnification 40fold). A large and irregular agglomeration of NCI-H526 cells in suspension is shown for comparison (C: magnification 40fold).