Table 4:
Recent studies regarding RFA for the treatment of lung metastases
| First author, year | Pts | Mts | Median diameter (cm), range | Histology | 90-day mortality | Morbidity | Median follow-up (months), range | 1-y OS | 3-y OS | 5-y OS |
|---|---|---|---|---|---|---|---|---|---|---|
| Gillams, 2013 | 122 | 398 | 1.7a (0.5–4) | Colon | 1/122 | 15% pnx drained 3.9% major complications |
12 (6–102) | NR | 57%b | NR |
| Chua, 2010 | 188 | 148 | 4a (SD ± 1) | Various | 0 | 30% pnx drained (1 pt operated for lung abscess) 11% pleural effusion |
29 (2–103) | NR | 60% | 45% |
| Yan, 2006 | 55 | 70c | 2.1a (SD ± 1.1) | Colon | 0 | 16% pnx drained 7% pleural effusion |
24 (6–40) | 85% | 46% | NR |
| Petre, 2013 | 45 | 69 | NR (0.4–3.5) | Colon | 0 | 19% pnx drained 4% pleural effusion |
18 (7–43) | 95% | 50% | NR |
| de Baère, 2015 | 566 | 642 | 1.5 (0.4–7) | Various | 2/566 | 58% pnx drained | 35 (20–53)d | 92% | 68% | 52% |
| Present report | 61 | 86 | 2 (0.7–5) | Various | 1/61 | 7.7% pnx drained (1 pt operated for prolonged air leak) 2% pleural effusion |
28 (2–126) | 95% | 49% | 45% |
Pts: number of treated patients; Mts: number of treated metastases; 1-y OS: 1-year overall survival; 3-y OS: 3-year overall survival; 5-y OS: 5-year overall survival; NR: not reported; RFA: radiofrequency ablation; SD: standard deviation.
aMean.
bCalculated from the first RFA treatment.
cTotal RFA.
dInterquartile.