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Reconstructions in 3D of a normal (A) and atubular (B) capsule showing changes in the nuclei of the parietal epithelial cells lining the capsule that are not apparent on two dimensional histologic sections. Glomeruli have been digitally removed. Sections correspond to Fig. 4(a) and 4(b), respectively. Block dimensions are approximately 400x400x150μm. Arrows in (A) indicate proximal tubule connection.
